netFormulary Joint Medicines Formulary NHS
Airedale NHS Foundation Trust
Airedale, Wharfedale and Craven CCG
 
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 Formulary Chapter 5: Infections - Full Chapter
Notes:

Within Airedale NHS Foundation Trust It is important to use antimicrobials in line with the antimicrobial use policy to

  • prevent unnecessary secondary infections, such as Clostridium difficile
  • Reduce the risk of resistance developing, so that future patients can receive the benefits of antimicrobials
  • Ensure the best outcomes for the patient
  • Not waste time and money on inappropriate therapy

Local guidance on the treatment of common infections is available and advice on antimicrobial therapy can be obtained from the Consultant Microbiologist, bleep via switchboard, or the Antimicrobial Lead Pharmacist, Kevin Frost via bleep 3091.

Within Airedale Wharfedale Craven CCG antimicrobial guidance can be found at this link - Summary of antimicrobial prescribing guidance - managing common infections

Unless explicitly stated, any brand names included in brackets next to a drug's generic name are there solely to aid searching and identification, and should not be considered to limit use to that specific brand.

Otitis media (acute): antimicrobial prescribing

 Details...
05.01.01  Penicillins
05.01.01.01  Benzylpenicillin and phenoxymethylpenicillin
Benzylpenicillin
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Formulary
Red
  • Benzylpenicillin Injection 
  • Link  Antibiotic Prescribing Guidance– Meningitis and Encephalitis (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance– Pneumonia and other Respiratory Tract Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  Surgical Antibiotic Prophylaxis and Treatment Guidance (ANHSFT access only)
       
    Phenoxymethylpenicillin
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    Formulary
    Green
  • Phenoxymethylpenicillin Oral Solution
  • Phenoxymethylpenicillin Tablets
     
  • Link  Adult Antibiotic Prescribing Guidance – Eye, Nose and Throat (ENT) infections - follow national guidance
    Link  Adult Antibiotic Prescribing Policy – Hyposplenia and Post-splenectomy treatment (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    Procaine Penicillin G Injection
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    Restricted Drug Restricted
    Red
  • Procaine penicillin G Vials

    For use on the recommendation of consultant microbiologist for the treatment of neuro syphyllis only. 
  • Link  BASHH guidelines on (neuro) syphillis (reference only - refer all patients to GUM)
       
    05.01.01.02  Penicillinase-resistant penicillins
    Flucloxacillin
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    Formulary Green Traffic Light Flucloxacillin Capsules
    Green Traffic Light Flucloxacillin Syrup
    Green Traffic Light Flucloxacillin Injection 
    Link  2016 update First Line Empirical Treatment of Infections wallchart (ANHST access only)
    Link  Adult Antibiotic Prescribing Policy - Musculoskeletal, Soft tissue and Skin Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance– Pneumonia and other Respiratory Tract Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  Surgical Antibiotic Prophylaxis and Treatment Guidance (ANHSFT access only)
    Link  UKMI QA: Can a 2 gram dose of flucloxacillin be given as a slow intravenous injection? (March 2014)
       
    05.01.01.03  Broad-spectrum penicillins
    Amoxicillin
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    Formulary Green Traffic Light Amoxicillin Capsules
    Green Traffic Light Amoxicillin SF Suspension

    Green <br>
Traffic Light Amoxicillin SF Sachets (Restricted)
  • Not recommended for endocarditis prophylaxis - NICE CG64.
  • For use only where high doses of amoxicillin required (e.g. bronchiectasis).

    Green Traffic Light Amoxicillin Injection

     
  • Link  2016 update First Line Empirical Treatment of Infections wallchart (ANHST access only)
    Link  Adult Antibiotic Prescribing Guidance – Eye, Nose and Throat (ENT) infections - follow national guidance
    Link  Adult Antibiotic Prescribing Policy – Urinary Tract Infections (ANHSFT access only)
    Link  Antibiotic Guidelines – Prophylaxis of Endocarditis (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance – Gastrointestinal Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance – Sepsis (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance– Meningitis and Encephalitis (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance– Pneumonia and other Respiratory Tract Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  Surgical Antibiotic Prophylaxis and Treatment Guidance (ANHSFT access only)
       
    Co-Amoxiclav
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    Restricted Drug Restricted Green Traffic Light Co-amoxiclav Tablets
    Green Traffic Light Co-amoxiclav SF Suspension
    Green Traffic Light Co-amoxiclav Injection

    Co-amoxiclav is associated with an increased risk of Clostridium difficile infection compared with other antibiotics. It should be used only in line with the antibiotics policy.
     
    Link  Adult Antibiotic Prescribing Policy - Musculoskeletal, Soft tissue and Skin Infections (ANHSFT access only)
       
    05.01.01.04  Antipseudomonal penicillins to top
    Pipericillin and Tazobactam
    (Tazocin®)
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    Restricted Drug Restricted
    Red
    Current global shortage of pipericillin-tazobactam. See below for suggested clinical alternatives during the shortage
    Link  2016 update First Line Empirical Treatment of Infections wallchart (ANHST access only)
    Link  Adult Antibiotic Prescribing Policy – Urinary Tract Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance – Gastrointestinal Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance – Sepsis (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance– Pneumonia and other Respiratory Tract Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  Neutropenic sepsis; diagnosis and management (ANHSFT access only)
    Link  NICE CG151: Neutropenic sepsis: prevention and management in people with cancer (Sept 2012)
       
    05.01.01.05  Mecillinams
    Pivmecillinam Hydrochloride
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    Formulary
    Green
  • Pivmecillinam Tablets

     
  • Link  Adult Antibiotic Prescribing Policy – Urinary Tract Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    05.01.02  Cephalosporins, carbapenems and other beta-lactams
     note 

    Cephalosporins are associated with an increased risk of Clostridium difficile infection compared with other antibiotics. They should be used only in line with the antibiotics policy.

    05.01.02  Cephalosporins
    Cefalexin
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    Formulary
    Green
  • Cefalexin Capsules
  • Cefalexin Syrup
     
  • Link  Adult Antibiotic Prescribing Policy – Urinary Tract Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    Cefuroxime
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    Formulary
    Red
  • Cefuroxime Injection (750mg strength vials)
     
  • Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  Surgical Antibiotic Prophylaxis and Treatment Guidance (ANHSFT access only)
       
    Cefaclor
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    Formulary
    Green
  • Cefaclor Capsules
  • Cefaclor Suspension
     
  • Link  2016 update First Line Empirical Treatment of Infections wallchart (ANHST access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    Cefixime
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    Restricted Drug Restricted
    Red
  • Cefixime Tablets

    Reserved for the treatment of gonorrhoea, on the advice of a consultant microbiologist only. 
  •    
    Cefotaxime
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    Formulary
    Red
  • Cefotaxime Injection 
  • Link  2016 update First Line Empirical Treatment of Infections wallchart (ANHST access only)
    Link  Adult Antibiotic Prescribing Policy – Urinary Tract Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance – Gastrointestinal Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance – Sepsis (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance– Meningitis and Encephalitis (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance– Pneumonia and other Respiratory Tract Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    Ceftazidime
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    Formulary
    Red
  • Ceftazidime Injection

     
  • Link  Antibiotic Prescribing Guidance– Pneumonia and other Respiratory Tract Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    Ceftriaxone
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    Formulary
    Green
  • Ceftriaxone Injection

     
  • Link  Adult Antibiotic Prescribing Policy - Musculoskeletal, Soft tissue and Skin Infections (ANHSFT access only)
    Link  Prescribing Guidance– Meningitis and Encephalitis (ANHSFT access only)
       
    05.01.02  Other beta-lactam antibiotics
    05.01.02.01  Cephalosporins to top
    05.01.02.02  Carbapenems
    Meropenem
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    Restricted Drug Restricted
    Red
  • Meropenem injection

     
  • Link  Antibiotic Prescribing Guidance – Endocarditis (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance – Gastrointestinal Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance – Sepsis (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  Neutropenic sepsis; diagnosis and management (ANHSFT access only)
       
    05.01.02.03  Other beta-lactams antibiotics
    Aztreonam (Azactam®)
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    Restricted Drug Restricted
    Red
  • Aztreonam Injection 
  • Link  Neutropenic sepsis; diagnosis and management (ANHSFT access only)
       
    05.01.03  Tetracyclines
    Oxytetracycline
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    First Choice
    Green
  • Oxytetracycline Tablets 
  • Doxycycline
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    Second Choice Green Traffic Light Doxycycline Capsules
    Green Traffic Light Doxycycline Dispersible Tablets
  • Doxycycline dispersible tablets are considerably more expensive than capsules

    Green Traffic Light Doxycycline Injection (Restricted)
  • Use supported for the treatment of malignant pleural effusions by Respiratory Consultant.
     
  • Link  Adult Antibiotic Prescribing Guidance – Eye, Nose and Throat (ENT) infections - follow national guidelines
    Link  Adult Antibiotic Prescribing Policy - Musculoskeletal, Soft tissue and Skin Infections (ANHSFT access only)
    Link  Adult Antibiotic Prescribing Policy – Urinary Tract Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance– Pneumonia and other Respiratory Tract Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    Tetracycline
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    Third Choice
    Green
  • Tetracycline Tablets  
  • Link  Antibiotic Prescribing Guidance – Gastrointestinal Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    Demeclocycline Hydrochloride
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    Restricted Drug Restricted
    Green
  • Demeclocycline Capsules

    Reserved for treatment of Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) 
  •    
    05.01.03  Tigecycline
    Tigecycline
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    Restricted Drug Restricted
    Red
  • Tigecycline Injection

    Restricted to prescribing by Consultant Microbiologist only. MHRA guidance states tigecycline must only be used where other agents are not suitable. 
  • Link  MHRA Drug Safety Update: Tigecycline (Tygacil▼): increased mortality in clinical trials (April 2011)
       
    05.01.04  Aminoglycosides to top
    Gentamicin
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    First Choice
    Red
  • Gentamicin Injection

    Guidance for Adult patients
    All treatment courses of Gentamicin should be prescribed on a Gentamicin prescription chart, available from the Pharmacy department, unless the patient is receiving therapy for endocarditis.

    2mg/kg prophylaxis doses (e.g. pre-operative prophylaxis, prophylaxis prior to catheter removal) should be prescribed on the inpatient chart.

    Guidance for all patients
    All patients receiving treatment courses of gentamicin should have daily urea and electrolyte blood tests and be monitored for signs of acute renal impairment. 
  • Neomycin
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    Restricted Drug Restricted
    Red
    • Neomycin tablets

    For the treatment of acute hepatic encephalopathy during inpatient stay

    Consultant Gastroenterologist use only

     
       
    Tobramycin
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    Restricted Drug Restricted
    Red
  • Tobramycin Injection

    Reserved for paediatric patients requiring an aminoglycoside on the recommendation or transfer from Leeds Teaching Hospitals NHS Trust 
  •    
    05.01.05  Macrolides
     note 

     

    Clarithromycin
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    First Choice Green Traffic Light Clarithromycin Tablets
    Green Traffic Light Clarithromycin Suspension
    Green Traffic Light Clarithromycin Injection in Sodium Chloride 
    Erythromycin
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    Second Choice Green Traffic Light Erythromycin Tablets
    Green Traffic Light Erythromycin Ethyl Succinate SF Suspension

    Green Traffic Light Erythromycin Lactobionate Injection (Restricted)
  • Reserved for aseptic unit only. Reserved for use as prokinetic agent in patients who are unable to take oral medication. 
  • Link  Adult Antibiotic Prescribing Guidance – Eye, Nose and Throat (ENT) infections - follow national guidance
    Link  Adult Antibiotic Prescribing Policy – Hyposplenia and Post-splenectomy treatment (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  UKMI Q&A: Is there an interaction between erythromycin and statins?
    Link  UKMI Q&A: What’s the optimal prokinetic dose of erythromycin in adults? (January 2017)
       
    Azithromycin
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    Restricted Drug Restricted
    Green
  • Azithromycin Suspension
  • Azithromycin Tablets

    Reserved for genitourinary medicine, treatment of pneumonia in paediatric patients with penicillin allergy, treatment of or suspected Mycoplasma/Chlamydia and COPD exacerbation prophylaxis. 
  • Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  Surgical Antibiotic Prophylaxis and Treatment Guidance (ANHSFT access only)
       
    05.01.06  Clindamycin
    Clindamycin
    View adult BNF View SPC online View childrens BNF  Track Changes
    Formulary Green Traffic Light Clindamycin Capsules
    Green Traffic Light Clindamycin Injection

     
    Link  Adult Antibiotic Prescribing Policy - Musculoskeletal, Soft tissue and Skin Infections (ANHSFT access only)
    Link  Adult Antibiotic Prescribing Policy – Urinary Tract Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  Surgical Antibiotic Prophylaxis and Treatment Guidance (ANHSFT access only)
       
    05.01.07  Some other antibacterials
    Rifaximin 550mg tablets (Targaxan®)
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    Restricted Drug Restricted
    Amber
    For Consultant Gastroenterologist use only for the prevention of recurrence of episodes of hepatic encephalopathy. Treatment will be initiated by a hospital specialist and continued in Primary Care, with a review by the specialist after 6 months. 
       
    Taurolidine citrate 4% (Taurolock®)
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    Formulary
    Red
    Approved for use for intravascular catheter salvage under the recommendation of microbiology 
       
    Taurolidine citrate 4% and heparin 500 units/mL (Taurolock HEP-500)
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    Formulary
    Red
    Approved for use for intravascular catheter salvage under the recommendation of microbiology 
       
    05.01.07  Chloramphenicol
    Chloramphenicol
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    Formulary
    Red
    Red Traffic Light Chloramphenicol Capsules
  • Consultant microbiologist recommendation only.
    Red Traffic Light Chloramphenicol Injection
  • Item not stocked in pharmacy but can be obtained on request 
  • Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    05.01.07  Fusidic acid to top
    Sodium fusidate
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    Formulary
    Amber
    Sodium Fusidate Tablets
  • Consultant microbiologist recommendation only
  • Not for use as monotherapy, as resistance will develop rapidly. 
  • Link  MHRA Drug Safety Update: Systemic fusidic acid and interaction with statins (Sept 2011)
       
    05.01.07  Vancomycin and teicoplanin
    Vancomycin
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    Formulary Green Traffic Light Vancomycin Injection

    Green Traffic Light Vancomycin Capsules (Restricted)
  • Reserved for 2nd line treatment of Clostridium Difficile

    Green Traffic Light Vancomycin Oral Solution (Restricted)
  • Product prepared to order by pharmacy.
  • Reserved for 2nd line treatment of Clostridium Difficile
     
  • Link  Antibiotic Prescribing Guidance – Gastrointestinal Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance– Pneumonia and other Respiratory Tract Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  Neutropenic sepsis; diagnosis and management (ANHSFT access only)
    Link  Surgical Antibiotic Prophylaxis and Treatment Guidance (ANHSFT access only)
       
    Colistimethate sodium
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    Restricted Drug Restricted

    Red

    • IV infusion

              Consultant microbiologist recommendation only

       

     Amber

    • Injection given via nebuliser

      For use under respiratory specialist recommendation only for the treatment for bronchiectasis.


       
      Due to the risk of neurotoxic and nephrotoxic side-effects to staff and other patients, nebulised colomycin must only be administered through a Side-Steam Plus device obtainable from Ward 7 stock).

      In inpatient areas, nebulisation ideally should take place in a side-room with an open window. Where another location must be used, the patient must be able to sit with the nebuliser with the door closed and the window open for the duration of the nebulisation. If administration does not occur in a side room, one hour should pass before the room is used by staff or other patients.
     
       
    Fosfomycin Sachets 3g (Monuril®)
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    Formulary
    Amber
    Reserved for the treatment of urinary tract infections associated with Extended-Spectrum Beta-Lactamase producing organisms (ESBLs) following advice from Microbiology

     
       
    Teicoplanin
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    Restricted Drug Restricted
    Red
  • Teicoplanin Injection

     
  • Link  Antibiotic Guidelines – Prophylaxis of Endocarditis (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  Surgical Antibiotic Prophylaxis and Treatment Guidance (ANHSFT access only)
       
    05.01.07  Daptomycin
    Daptomycin
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    Restricted Drug Restricted
    Red
  • Daptomycin Injection

    Restricted for prescribing by Consultant Microbiologist or for the use by the Airedale Collaborative Care team in the treatment of outpatients with penicillin allergy for cellulitis 
  • Link  Adult Antibiotic Prescribing Policy - Musculoskeletal, Soft tissue and Skin Infections (ANHSFT access only)
       
    05.01.07  Linezolid
    Linezolid
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    Restricted Drug Restricted
    Red
  • Linezolid Tablets

    Linezolid is a third line antibiotic, to be used only with the agreement of Consultant Microbiologist’s and a senior pharmacist.
    Potential for the development of resistance, side effects, interactions and it’s high cost mean this antibiotic should be reserved for infections resistant to or non-responsive to vancomycin.
    Patients should be is monitored for blood dyscrasias (weekly FBC) and interactions (Linezolid shares MAOI interactions).
    Other serious side effects can occur with medium to long-term use(>14 days).
     
  •    
    05.01.07  Quinupristin and dalfopristin
    05.01.07  Polymyxins to top
    05.01.08  Sulphonamides and trimethoprim
    Trimethoprim
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    First Choice
    Green
  • Trimethoprim Tablets
  • Trimethoprim SF Suspension

  • To minimise the incidence of gram-negative bloodstream infection, GPs and other primary care prescribers are being encouraged to use nitrofurantoin first-line, as opposed to trimethoprim
  • In secondary care, trimethoprim remains the first-line option for treatment of UTIs in patients who have not previously received treatment for UTIs as per local guidance (see below - ANHSFT access only)  
  • Co-trimoxazole
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    Restricted Drug Restricted Green Traffic Light Co-trimoxazole Tablets
    Green Traffic Light Co-trimoxazole Syrup
  • Reserved for prophylaxis and treatment of Pneumocystis carnii Pneumonia (PCP) and prophylaxis of spontaneous bacterial peritonitis

    Green Traffic Light Co-trimoxazole Injection
  • Reserved for prophylaxis and treatment of Pneumocystis carnii Pneumonia (PCP).
  • NB: This product has a short expiry once reconstituted.

     
  • Link  Antibiotic Prescribing Guidance – Gastrointestinal Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    05.01.09  Antituberculosis drugs
     note  All suspected cases of tuberculosis should be referred to one of Respiratory Consultants for assessment. Three morning sputum samples are essential in attempting to obtain microbiological diagnosis.

    Ethambutol
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    Formulary
    Red
  • Ethambutol Tablets  
  •    
    Isoniazid
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    Formulary
    Red
  • Isoniazid Elixir
  • Isoniazid Injection
  • Isoniazid Tablets
     
  •    
    Pyrazinamide
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    Formulary
    Red
  • Pyrazinamide Tablets

    Available from IDIS on a Named Patient Basis only. The appropriate forms will need to be filled in by a consultant. 
  •    
    Rifampicin
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    Formulary
  • Rifampicin Capsules
  • Rifampicin Syrup
  • Rifampicin Infusion

    Red Traffic Light  Restricted to hospital specialist only when used for the treatment of Tuberculosis.
    Amber Traffic Light  For meningitis prophylaxis under the recommendation of the Health Protection Authority, or severe infections under the recommendation of a consultant microbiologist

  • Not for use as monotherapy, as resistance will develop rapidly. 
  • Link  Antibiotic Prescribing Guidance – Endocarditis (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance– Pneumonia and other Respiratory Tract Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    Rifampicin, isoniazid, pyrazinamide, ethambutol hydrochloride (Voractiv®)
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    Restricted Drug Restricted
    Red
  • Voractiv® tablets (rifampicin/isoniazid/pyrazinamide/ethambutol)

    For the treatment of tuberculosis. 
  •    
    05.01.10  Antileprotic drugs
     note 

    Please seek expert advice from the Consultant Microbiologist for treatment of all tropical diseases.

    Dapsone
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    Restricted Drug Restricted
    Amber
    Dapsone Tablets

  • For second-line prophylaxis of Pneumocystis pneumonia (PCP), in patients who are unable to take co-trimoxazole.
  • Specialist recommendation only 
  •    
    05.01.11  Metronidazole and tinidazole
    Metronidazole
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    Formulary Green Traffic Light Metronidazole Suspension
    Green Traffic Light Metronidazole Suppositories
    Green Traffic Light Metronidazole Tablets
    Green Traffic Light Metronidazole Infusion

     
    Link  2016 update First Line Empirical Treatment of Infections wallchart (ANHST access only)
    Link  Adult Antibiotic Prescribing Guidance – Eye, Nose and Throat (ENT) infections - follow national guidance
    Link  Adult Antibiotic Prescribing Policy - Musculoskeletal, Soft tissue and Skin Infections (ANHSFT access only)
    Link  Adult Antibiotic Prescribing Policy – Urinary Tract Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance – Gastrointestinal Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance – Sepsis (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance– Pneumonia and other Respiratory Tract Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  Surgical Antibiotic Prophylaxis and Treatment Guidance (ANHSFT access only)
       
    05.01.12  Quinolones to top
     note 

    An information leaflet to inform patients about the possible side effects of quinolones on tendons, muscles, joints and nerves is available at this link.

    Quinolones are associated with an increased risk of Clostridium difficile infection compared with other antibiotics. They should be used only in line with the antibiotics policy.

    Disabling, long-lasting and potentially irreversible side effects have been reported very rarely with fluoroquinolone antibiotics (ciprofloxacin, levofloxacin, moxifloxacin and ofloxacin) as follows:

     

     

    Fluoroquinolones should only be prescribed where other antibiotics are considered inappropriate - i.e. ineffective response to, resistance to, intolerance of or contraindication to specified first-line antibiotics stated in ANHSFT Adult Antimicrobial Prescribing Guidance or NICE Primary Care Guidance after careful assessment of the benefits and risks and consideration of other therapeutic options.  Due to the risk of arthropathy, the use of quinolones in children is extremely limited.

     

    Where a quinolone is still considered the preferred treatment option, the patient must be counselled by the prescriber about potential adverse effects and the actions to take should these occur.  This counselling and the rationale for use must be documented in the patient’s care record.

     

    Tendon damage: Fluoroquinolones should be used with caution in patients >60 years, patients with renal impairment or solid organ transplants as these groups are at a higher risk of tendon injury. Use should be avoided in patients who have previously experienced a serious adverse effect with a fluoroquinolone or in patients taking concomitant corticosteroids. Treatment must be discontinued at the first sign of tendonitis and the affected limb(s) appropriately treated.

    Ciprofloxacin
    View adult BNF View SPC online View childrens BNF  Track Changes
    Formulary Green Traffic Light Ciprofloxacin Tablets
    Green Traffic Light Ciprofloxacin Suspension

    Green Traffic Light Ciprofloxacin infusion (Restricted)
  • Only for use in patients that cannot take oral ciprofloxacin. There is absolutely no benefit over oral formulations otherwise.
     
  • Link  Adult Antibiotic Prescribing Policy - Musculoskeletal, Soft tissue and Skin Infections (ANHSFT access only)
    Link  Adult Antibiotic Prescribing Policy – Urinary Tract Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance – Endocarditis (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance – Gastrointestinal Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance– Pneumonia and other Respiratory Tract Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  DSU: Fluoroquinolone antibiotics: new restrictions and precautions for use due to very rare reports of disabling and potentially long-lasting or irreversible side effects (March 2019)
    Link  DSU: Systemic and inhaled fluoroquinolones: small increased risk of aortic aneurysm and dissection; advice for prescribing in high-risk patients
    Link  Surgical Antibiotic Prophylaxis and Treatment Guidance (ANHSFT access only)
       
    Levofloxacin
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted Green Traffic Light Levofloxacin Tablets
    Green Traffic Light Levofloxacin Infusion 
    Link  Antibiotic Prescribing Guidance – Gastrointestinal Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidance– Pneumonia and other Respiratory Tract Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  DSU: Fluoroquinolone antibiotics: new restrictions and precautions for use due to very rare reports of disabling and potentially long-lasting or irreversible side effects (March 2019)
    Link  DSU: Systemic and inhaled fluoroquinolones: small increased risk of aortic aneurysm and dissection; advice for prescribing in high-risk patients
    Link  Neutropenic sepsis; diagnosis and management (ANHSFT access only)
       
    Ofloxacin
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Green
  • Ofloxacin Tablets

     
  • Link  Adult Antibiotic Prescribing Policy – Urinary Tract Infections (ANHSFT access only)
    Link  DSU: Fluoroquinolone antibiotics: new restrictions and precautions for use due to very rare reports of disabling and potentially long-lasting or irreversible side effects (March 2019)
    Link  DSU: Systemic and inhaled fluoroquinolones: small increased risk of aortic aneurysm and dissection; advice for prescribing in high-risk patients
       
    05.01.13  Urinary-tract infections
    Nitrofurantoin
    View adult BNF View SPC online View childrens BNF  Track Changes
    Formulary
    Green
  • Nitrofurantoin Tablets
  • Nitrofurantoin Capsules
  • Nitrofurantoin MR Capsules
  • Nitrofurantoin Suspension

  • To minimise the incidence of gram-negative bloodstream infection, GPs and other primary care prescribers are being encouraged to use nitrofurantoin first-line, as opposed to trimethoprim
  • In secondary care, trimethoprim remains the first-line option for treatment of UTIs in patients who have not previously received treatment for UTIs as per local guidance (see below - ANHSFT access only)
  • Please note: Nitrofurantoin suspension is very expensive. Consult pharmacy if your patient requires a liquid preparation, as alternative options may be more appropriate. 
  • Link  Adult Antibiotic Prescribing Policy – Urinary Tract Infections (ANHSFT access only)
    Link  ANHSFT Urinary and Genito-urinary Tract Infection Guidelines (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  MHRA Drug safety Update: Nitrofurantoin now contraindicated in most patients with an estimated glomerular filtration rate (eGFR) of less than 45 ml/min/1.73m2 (Sept 2014)
       
    05.02  Antifungal drugs
     note  Antifungal medicines should be used in line with the antifungal medicines prescribing guidance.
    Fluconazole
    View adult BNF View SPC online View childrens BNF  Track Changes
    Formulary Green Traffic Light Fluconazole Capsules
    Green Traffic Light Fluconazole Suspension
    Green Traffic Light Fluconazole Injection
    Green Traffic Light Fluconazole Infusion

     
    Link  Adult Antibiotic Prescribing Policy – Urinary Tract Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidelines – Invasive Fungal Infections (ANHSFT access only)
    Link  Antibiotic Prescribing Guidelines – Superficial Fungal Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    Amphotericin
    View adult BNF View SPC online View childrens BNF  Track Changes
    Formulary Green Traffic Light Amphotericin SF Suspension
    Green Traffic Light Amphotericin Liposomal Injection
     
    Link  Antibiotic Prescribing Guidelines – Invasive Fungal Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  Drug Safety Update: Parenteral amphotericin B: reminder of risk of potentially fatal adverse reaction if formulations confused
       
    Voriconazole
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
  • Voriconazole Tablets

    Oral use supported for the treatment of systemic fungal infections 2nd line after amphotericin B 
  • Link  Antibiotic Prescribing Guidelines – Invasive Fungal Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    Caspofungin
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
  • Caspofungin Infusion

    Use supported for systemic fungal infections third line after amphotericin B and oral voriconazole 
  • Link  Antibiotic Prescribing Guidelines – Invasive Fungal Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    Flucytosine (Ancotil®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
  • Flucytosine Infusion

    Restricted for the treatment of cryptococcosis meningitis under the advice of a consultant microbiologist.

     
  • Link  Antibiotic Prescribing Guidelines – Invasive Fungal Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    Griseofulvin
    View adult BNF View SPC online View childrens BNF  Track Changes
    Formulary
    Green
  • Griseofulvin Suspension
  • Griseofulvin Tablets  
  • Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    Terbinafine
    View adult BNF View SPC online View childrens BNF  Track Changes
    Formulary
    Green
  • Terbinafine Tablets 
  • Link  Antibiotic Prescribing Guidelines – Superficial Fungal Infections (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    05.03  Antiviral drugs
    05.03.01  HIV infection
     note  The management of HIV infection requires specialist input Airedale NHS Foundation Trust formulary does not include these medicines, aside from their use as post-exposure prophylaxis.
    Lopinavir with Ritonavir (Kaletra®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
    For use as part of HIV post-exposure prophylaxis regimen, stock is held in accident and emergency 
    Link  DSU: Ritonavir-containing products: reports of interaction with levothyroxine leading to reduced thyroxine levels
       
    05.03.01  Nucleoside reverse transcriptase inhibitors to top
    Didanosine
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
  • Didanosine E/C Capsules
  • Didanosine Tablets

    Reserved for patients as part of a HIV treatment plan under a HIV specialist consultant  
  •    
    Zidovudine
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
  • Zidovudine Capsules
  • Zidovudine SF Solution

    Reserved for patients as part of a HIV treatment plan under a HIV specialist consultant
     
  •    
    05.03.01  Other antiretrovirals
    05.03.02  Herpesvirus infections
    05.03.02.01  Herpes simplex and varicella-zoster infection
    Aciclovir
    View adult BNF View SPC online View childrens BNF  Track Changes
    Formulary Green Traffic Light Aciclovir SF Suspension
    Green Traffic Light Aciclovir Dispersible Tablets
    Green Traffic Light Aciclovir Injection

     
    Link  Antibiotic Prescribing Guidance– Meningitis and Encephalitis (ANHSFT access only)
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    05.03.02.02  Cytomegalovirus infrection
    Ganciclovir
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
  • Ganciclovir Injection

    Under Consultant Microbiologist recommendation only 
  • Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    05.03.03  Viral hepatitis to top
    05.03.03.01  Chronic hepatitis B
    Entecavir (Baraclude®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
    High Cost Medicine
    For the treatment of Hepatitis B in line with NICE TA153. 
    Link  NICE TA153: Entecavir for the treatment of chronic hepatitis B (Aug 2008)
       
    Tenofovir Disproxil
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
    Use supported for the treatment of patients with chronic hepatitis B in adults with compensated liver disease in-line with NICE TA173 Consultant Gastroenterologist use only. 
    Link  NICE TA173: Tenofovir disoproxil for the treatment of chronic hepatitis B (July 2009)
       
    05.03.03.02  Chronic hepatitis C
    Boceprevir (Victrellis®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
    High Cost Medicine
  • Boceprevir Capsules

    Use supported for the treatment of hepatitis C (genotype 1) in combination with peginterferon and ribavirin in-line with NICE TA 253 (April 2012). Use restricted to the Consultant Gastroenterologists.

    Funding to be agreed with NHSE
    Blueteq® registration and approval for use is required for this product before it may be dispensed.  
  • Link  NICE TA253: Boceprevir for the treatment of genotype 1 chronic hepatitis C (April 2012)
       
    Daclatasvir (Daklinza®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
    High Cost Medicine
  • Daclatasvir (Daklinza®)

    For the treatment of hepatitis C in line with NICE TA364. Use restricted to Consultant Gastroenterologists only.
    Blueteq® registration and approval for use is required for this product before it may be dispensed.  
  • Link  DSU: Direct-acting antivirals for chronic hepatitis C: risk of hypoglycaemia in patients with diabetes (December 2018)
    Link  MHRA Drug Safety Update: Direct-acting antiviral interferon-free regimens to treat chronic hepatitis C: risk of hepatitis B reactivation
    Link  MHRA Drug Safety Update: Direct-acting antivirals to treat chronic hepatitis C: risk of interaction with vitamin K antagonists and changes in INR
    Link  NICE TA364: Daclatasvir for treating chronic hepatitis C (November 2015)
       
    Dasabuvir (Exviera®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
    High Cost Medicine
  • Dasabuvir (Exviera®)

    For the treatment of hepatitis C in line with NICE TA365. Use restricted to Consultant Gastroenterologists only.
    Blueteq® registration and approval for use is required for this product before it may be dispensed.  
  • Link  DSU: Direct-acting antivirals for chronic hepatitis C: risk of hypoglycaemia in patients with diabetes (December 2018)
    Link  MHRA Drug Safety Update: Direct-acting antiviral interferon-free regimens to treat chronic hepatitis C: risk of hepatitis B reactivation
    Link  MHRA Drug safety Update: Direct-acting antivirals to treat chronic hepatitis C: risk of interaction with vitamin K antagonists and changes in INR
    Link  NICE TA365: Ombitasvir-paritaprevir-ritonavir with or without dasabuvir for treating chronic hepatitis C (Nov 2015)
       
    Elbasvir-grazoprevir (Zepatier®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
    High Cost Medicine
    For the treatment of hepatitis C in line with NICE TA413. Use restricted to Consultant Gastroenterologists only.
    Blueteq® registration and approval for use is required for this product before it may be dispensed.  
    Link  DSU: Direct-acting antivirals for chronic hepatitis C: risk of hypoglycaemia in patients with diabetes (December 2018)
    Link  NICE TA413: Elbasvir–grazoprevir for treating chronic hepatitis C (Oct 2016)
       
    Glecaprevir/pibrentasvir tablets
    (Maviret®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
  • Glecaprevir/pibrentasvir tablets

    For the treatment of hepatitis C in-line with NHS England commissioning.
    Use restricted to Consultant Gastroenterologists only.
    Blueteq® registration and approval for use is required for this product before it may be dispensed.  
  • Link  DSU: Direct-acting antivirals for chronic hepatitis C: risk of hypoglycaemia in patients with diabetes (December 2018)
    Link  NICE TA499: Glecaprevir–pibrentasvir for treating chronic hepatitis C (January 2018)
       
    Ombistavir/paritaprevir/ritonavir  (Viekirax®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
    High Cost Medicine
  • Ombistavir/paritaprevir/ritonavir (Viekirax®)

    For the treatment of hepatitis C in line with NICE TA365. Use restricted to Consultant Gastroenterologists only.
    Blueteq® registration and approval for use is required for this product before it may be dispensed.  
  • Link  DSU: Direct-acting antivirals for chronic hepatitis C: risk of hypoglycaemia in patients with diabetes (December 2018)
    Link  MHRA Drug Safety Update: Direct-acting antiviral interferon-free regimens to treat chronic hepatitis C: risk of hepatitis B reactivation
    Link  MHRA Drug safety Update: Direct-acting antivirals to treat chronic hepatitis C: risk of interaction with vitamin K antagonists and changes in INR
    Link  MHRA Drug Safety Update: Ritonavir-containing products: reports of interaction with levothyroxine leading to reduced thyroxine levels
    Link  NICE TA365: Ombitasvir-paritaprevir-ritonavir with or without dasabuvir for treating chronic hepatitis C (November 2015)
       
    Ribavirin
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
  • Ribavirin Capsules

    Reserved for the treatment of hepatitis C in combination with Peginterferon under the recommendation of Consultant Gastroenterologists 
  • Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  NICE TA200: Peginterferon alfa and ribavirin for the treatment of chronic hepatitis C (Sept 2010)
       
    Simeprevir (Olysio®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
    High Cost Medicine
  • Simeprevir Capsules

    For use by the Gastroenterologists for the treatment of chronic hepatitis C in combination with ribavirin and pegylated interferon only if funding is agreed by NHSE.
    Blueteq® registration and approval for use is required for this product before it may be dispensed.  
  • Link  MHRA Drug Safety Update: Direct-acting antiviral interferon-free regimens to treat chronic hepatitis C: risk of hepatitis B reactivation
    Link  MHRA Drug safety Update: Direct-acting antivirals to treat chronic hepatitis C: risk of interaction with vitamin K antagonists and changes in INR
    Link  MHRA Drug Safety Update: Simeprevir with sofosbuvir: risk of severe bradycardia and heart block when taken with amiodarone
       
    Sofosbuvir (Sovaldi®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
    High Cost Medicine
    Use supported for the treatment of hepatitis C in-line with NICE TA 330. Use restricted to Consultant Gastroenterologists only.
    Blueteq® registration and approval for use is required for this product before it may be dispensed.  
    Link  NICE TA330 Sofosbuvir for treating chronic hepatitis C (Feb 2015)
    Link  DSU: Direct-acting antivirals for chronic hepatitis C: risk of hypoglycaemia in patients with diabetes (December 2018)
    Link  MHRA Drug Safety Update: Direct-acting antiviral interferon-free regimens to treat chronic hepatitis C: risk of hepatitis B reactivation
    Link  MHRA Drug safety Update: Direct-acting antivirals to treat chronic hepatitis C: risk of interaction with vitamin K antagonists and changes in INR
    Link  MHRA Drug Safety Update: Simeprevir with sofosbuvir: risk of severe bradycardia and heart block when taken with amiodarone
       
    Sofosbuvir/ledipasvir (Harvoni®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
    High Cost Medicine
  • Sofosbuvir/ledipasvir (Harvoni®)

    For the treatment of hepatitis C in line with NICE TA363. Use restricted to Consultant Gastroenterologists only.
    Blueteq® registration and approval for use is required for this product before it may be dispensed.  
  • Link  DSU: Direct-acting antivirals for chronic hepatitis C: risk of hypoglycaemia in patients with diabetes (December 2018)
    Link  DSU: Direct-acting antivirals for chronic hepatitis C: risk of hypoglycaemia in patients with diabetes (December 2018)
    Link  MHRA Drug Safety Update: Direct-acting antiviral interferon-free regimens to treat chronic hepatitis C: risk of hepatitis B reactivation
    Link  MHRA Drug safety Update: Direct-acting antivirals to treat chronic hepatitis C: risk of interaction with vitamin K antagonists and changes in INR
    Link  NICE TA363: Ledipasvir-sofosbuvir for treating chronic hepatitis C (November 2015)
       
    Sofosbuvir/velpatasvir (Epclusa®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
  • Sofosbuvir/velpatasvir (Epclusa®)

    For the treatment of hepatitis C in line with NICE TA430. Use restricted to Consultant Gastroenterologists only.
    Blueteq® registration and approval for use is required for this product before it may be dispensed.  
  • Link  DSU: Direct-acting antivirals for chronic hepatitis C: risk of hypoglycaemia in patients with diabetes (December 2018)
    Link  NICE TA430: Sofosbuvir-velpatasvir for treating chronic hepatitis C (January 2017)
       
    Sofosbuvir-velpatasvir-voxilaprevir  (Vosevi®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
    • Sofosbuvir-velpatasvir-voxilaprevir (Vosevi®)

      Use supported for the treatment of chronic hepatitis C in-line with NICE TA507 and NHS England commissioning criteria. Use restricted to the Consultant Gastroenterologists.
      Blueteq® registration and approval for use is required for this product before it may be dispensed.
     
    Link  DSU: Direct-acting antivirals for chronic hepatitis C: risk of hypoglycaemia in patients with diabetes (December 2018)
    Link  NICE TA507: Sofosbuvir–velpatasvir–voxilaprevir for treating chronic hepatitis C
       
    Telaprevir  (Incivo®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
    High Cost Medicine
  • Telaprevir Tablets

    Use supported for the treatment of hepatitis C (genotype 1) in combination with peginterferon and ribavirin in-line with NICE TA 253 (April 2012). Use restricted to the Consultant Gastroenterologists.
    Blueteq® registration and approval for use is required for this product before it may be dispensed.  
  • Link  NICE TA252: Telaprevir for the treatment of genotype 1 chronic hepatitis C (April 2012)
       
    05.03.04  Influenza
     note 

    PHE guidance on use of antiviral agents for the treatment and prophylaxis of seasonal influenza (September 2019)

    Oseltamivir (Tamiflu®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Green
  • Oseltamivir Capsules
  • Oseltamivir Suspension

    Reserved for prophylaxis and treatment of seasonal influenza when NICE guidance is active (See technology appraisals TA158 and TA168) 
  • Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
    Link  MHRA Drug safety Update: Oseltamivir changed concentration and dosing dispenser of oral suspension (Oct 2012)
       
    Zanamivir (Relenza®)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted

    Green Zanamivir capsules for inhalation and diskhaler.

    Reserved for prophylaxis and treatment of seasonal influenza when NICE guidance is active (See technology appraisals TA158 and TA168)

    Red Zanamivir infusion

    For the treatment of complicated influenza in-line with Public Health England Guidance

    Consultant Microbiologist use only

     
    Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    05.03.05  Respiratory syncytial virus
    Palivizumab
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
  • Palivizumab Injection

    Consultant Paediatrician use only
    Blueteq® registration and approval for use is required for this product before it may be dispensed.  
  • Link  Antimicrobial Prescribing Guidance for Adults (ANHSFT access only)
       
    Ribavirin
    (Inhalation)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Restricted Drug Restricted
    Red
  • Ribavirin Inhalation

    Consultant Paediatrician use only 
  •    
    05.04  Antiprotozoal drugs to top
    05.04.01  Antimalarials
    05.04.01  Treatment of malaria
    05.04.01  Falciparum malaria (treatment)
    05.04.01  Benign malarias (treatment)
    05.04.01  Prophylaxis against malaria to top
    05.04.01  Specific recommendations
    05.04.01  Artemether with lumefabtrine
    05.04.01  Chloroquine
    Chloroquine
    View adult BNF View SPC online View childrens BNF  Track Changes
    Formulary
    Red
  • Chloroquine Syrup
  • Chloroquine Tablets

    Malaria prophylaxis is available Over the Counter or on Private Prescription. See links above for travel websites. 
  •    
    05.04.01  Mefloquine
    05.04.01  Primaquine to top
    Primaquine
    View adult BNF View SPC online View childrens BNF  Track Changes

    Red ULM
  • Primaquine Tablets

    Malaria prophylaxis is available Over the Counter or on Private Prescription. See links above for travel websites. 
  • Link  Unlicensed medicine request form needs to be filled in for new patients
       
    05.04.01  Proguanil
    Proguanil Hydrochloride
    View adult BNF View SPC online View childrens BNF  Track Changes
    Formulary
    Red
  • Proguanil Tablets

    Malaria prophylaxis is available Over the Counter or on Private Prescription. See links above for travel websites. 
  •    
    05.04.01  Pyrimethamine
    05.04.01  Quinine
    Quinine
    (malaria)
    View adult BNF View SPC online View childrens BNF  Track Changes
    Formulary
    Red
  • Quinine Sulphate Tablets

    Malaria prophylaxis is available Over the Counter or on Private Prescription. See links above for travel websites. 
  •    
    05.04.01  Tetracyclines
    05.04.02  Amoebicides to top
     note  The Airedale NHS Trust formulary does not cover medicines in these BNF categories. Please seek expert advice from the consultant microbiologist for treatment of these infections
    05.04.03  Trichomonacides
     note  The Airedale NHS Trust formulary does not cover medicines in these BNF categories. Please seek expert advice from the consultant microbiologist for treatment of these infections
    05.04.04  Antigiardial drugs
     note  The Airedale NHS Trust formulary does not cover medicines in these BNF categories. Please seek expert advice from the consultant microbiologist for treatment of these infections
    05.04.05  Leishmaniacides
     note  The Airedale NHS Trust formulary does not cover medicines in these BNF categories. Please seek expert advice from the consultant microbiologist for treatment of these infections
    05.04.06  Trypanocides
     note  The Airedale NHS Trust formulary does not cover medicines in these BNF categories. Please seek expert advice from the consultant microbiologist for treatment of these infections
    05.04.07  Drugs for toxoplasmosis to top
     note  The Airedale NHS Trust formulary does not cover medicines in these BNF categories. Please seek expert advice from the consultant microbiologist for treatment of these infections
    05.04.08  Drugs for pneumocystis pneumonia
     note  The Airedale NHS Trust formulary does not cover medicines in these BNF categories. Please seek expert advice from the consultant microbiologist for treatment of these infections.

    Co-trimoxazole and dapsone are used in the prophylaxis of pneumocystis pneumonia in high-risk patients.
    05.04.08  Treatment
    05.04.08  Prophylaxis
    05.05  Anthelmintics
    05.05.01  Drugs for threadworms to top
    Mebendazole
    View adult BNF View SPC online View childrens BNF  Track Changes
    Formulary
    Green
  • Mebendazole Suspension
  • Mebendazole Tablets

     
  • Link  Antibiotic Prescribing Guidance – Gastrointestinal Infections (ANHSFT access only)
       
    05.05.02  Ascaricides
     note  The Airedale NHS Trust formulary does not cover medicines in these BNF categories. Please seek expert advice from the Consultant Microbiologist for treatment of these infections.
    05.05.03  Drugs for tapeworm infections
     note  The Airedale NHS Trust formulary does not cover medicines in these BNF categories. Please seek expert advice from the Consultant Microbiologist for treatment of these infections.
    05.05.03  Taenicides
    05.05.03  Hydatid disease
    05.05.04  Drugs for hookworms to top
     note  The Airedale NHS Trust formulary does not cover medicines in these BNF categories. Please seek expert advice from the Consultant Microbiologist for treatment of these infections.
    Levamisole
    (Suspension)
    View adult BNF View SPC online View childrens BNF  Track Changes

    Red ULM
    • Levamisole 50mg/5mL Oral Suspension

    For initiation by Tertiary Centres for Paediatric Nephrotic Syndrome.

     
    Link  Regional Guideline on the Management of Nephrotic Syndrome in Childhood
    Link  Unlicensed Medicines Consultant Request Form (ANHSFT access only)
    Link  Unlicensed Medicines Patient Agreement for Use Form (ANHSFT access only)
    Link  Unlicensed Medicines Patient Information Leaflet (ANHSFT access only)
    Link  Unlicensed Medicines Policy (ANHSFT access only)
       
    05.05.05  Schistosomicides
     note  The Airedale NHS Trust formulary does not cover medicines in these BNF categories. Please seek expert advice from the Consultant Microbiologist for treatment of these infections.
    05.05.06  Filaricides
     note  The Airedale NHS Trust formulary does not cover medicines in these BNF categories. Please seek expert advice from the Consultant Microbiologist for treatment of these infections.
    05.05.07  Drugs for cutaneous larva migrans
     note  The Airedale NHS Trust formulary does not cover medicines in these BNF categories. Please seek expert advice from the Consultant Microbiologist for treatment of these infections.
    05.05.08  Drugs for strongyloidiasis
     note  The Airedale NHS Trust formulary does not cover medicines in these BNF categories. Please seek expert advice from the Consultant Microbiologist for treatment of these infections.
     ....
     Non Formulary Items
    HIV Pre-Exposure Prophylaxis  (PrEP)

    View adult BNF View SPC online View childrens BNF Track Changes
    Non Formulary
    Black
    Not routinely commissioned pending national policy decision from NHS England.
     
      
    Key
    note Notes
    Section Title Section Title (top level)
    Section Title Section Title (sub level)
    First Choice Item First Choice item
    Non Formulary Item Non Formulary section
    Restricted Drug
    Restricted Drug
    Unlicensed Drug
    Unlicensed
    Track Changes
    Display tracking information
    click to search medicines.org.uk
    Link to adult BNF
    click to search medicines.org.uk
    Link to children's BNF
    click to search medicines.org.uk
    Link to SPCs
    Cytotoxic Drug
    Cytotoxic Drug
    CD
    Controlled Drug
    High Cost Medicine
    High Cost Medicine
    Cancer Drugs Fund
    Cancer Drugs Fund
    NHSE
    NHS England
    Homecare
    Homecare
    CCG
    CCG

    Traffic Light Status Information

    Status Description

    Green

    Green - Drugs suitable for generalised use in accordance with position summary. Inform primary care of need to prescribe using a TTO chart if in patient or Treatment Advice Note (TAN) if Outpatient.   

    Amber

    Amber - these drugs require specialist initiation or recommendation  

    Amber SCG

    Amber Share Care - Drugs suitable for generalist use, in accordance with position summary, normally following specialist initiation and stabilisation. Ongoing division of responsibility for drug and disease monitoring between specialist and GP by a Shared Care Guideline (SCG). If no SCG in place status reverts to red.  

    Red

    Red - Drugs for specialist use only, in accordance with position summary. GP’s should not be asked to prescribe these products.  

    Red ULM

    Red ULM - Unlicensed medicines for specialist use only, in accordance with position summary. GP’s should not be asked to prescribe these products.  

    Grey

    Grey drugs - No formal commissioning position. Check appropriate CCG /NHSE commissioning list or contact CCG/NHSE Medicines Management team for advice. Fill in individual funding request for appropriate CCG/NHSE. This will need to be signed by the Chief Pharmacist and a copy of the relevant DTC submission attached.   

    Black

    Black - Drugs not routinely commissioned so should not usually be prescribed  

    netFormulary