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Airedale NHS Foundation Trust
Airedale, Wharfedale and Craven CCG
 
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 Formulary Chapter 8: Malignant disease and immunosuppression - Full Chapter
Notes:
Unless explicitly stated, any brand names included in brackets next to a drug's generic name are there solely to aid searching and identification, and should not be considered to limit use to that specific brand.  
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08.02.01  Expand sub section  Antiproliferative immunosuppressants
Azathioprine
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Formulary Amber Traffic Light Azathioprine Tablets
Red Traffic Light Azathioprine injection 
Link  Azathioprine and Mercaptopurine Gastroenterology Shared Care Guideline
Link  Azathioprine Rheumatology Shared Care Guideline
Link  Link to Leeds Share Care Guideline: Adult liver transplant
Link  Link to Leeds Shared Care Guideline: Adult renal transplant
 
Mycophenolate Mofetil
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Restricted Drug Restricted
Amber SCG
  • Mycophenolate Mofetil Capsules
  • Mycophenolate mofetil 1gram/5ml suspension

    Prophylaxis of acute renal, cardiac or hepatic transplant rejection (in combination with ciclsporin and corticosteroids) under specialist supervision

    Also supported for use by consultants for the following specialties (unlicensed uses):

    1. Rheumatology - Usually considered in active SLE or other serious connective tissue diseases and vasculitides
    2. Gastroenterology – considered in very occasional inflammatory bowel disease patients and autoimmune hepatitis
    3. Neurology – usually considered in myasthenia gravis as steroid sparing agent.
    4. Respiratory
    a. idiopathic pulmonary fibrosis intolerant to azathioprine often awaiting lung transplant
    b. pulmonary vasculitides (Wegner’s granulomatosis, CSS and microscopic polyangitis)
 
Link  DSU: Mycophenolate mofetil, mycophenolic acid: updated contraception advice for male patients (February 2018)
Link  MHRA Drug Safety Update: Mycophenolate mofetil (CellCept) and mycophenolic acid: risk of hypogammaglobulinaemia and risk of bronchiectasis (January 2015)
Link  MHRA Drug Safety Update: Mycophenolate mofetil, mycophenolic acid: new pregnancy-prevention advice for women and men (December 2015)
Link  Mycophenolate mofetil Shared Care Guideline
Link  NICE TA85 - Immunosuppressive therapy for renal transplantation in adults (September 2004)
 
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Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Green

Green - Drugs suitable for generalised use in accordance with position summary. Inform primary care of need to prescribe using a TTO chart if in patient or Treatment Advice Note (TAN) if Outpatient.   

Amber

Amber - these drugs require specialist initiation or recommendation  

Amber SCG

Amber Share Care - Drugs suitable for generalist use, in accordance with position summary, normally following specialist initiation and stabilisation. Ongoing division of responsibility for drug and disease monitoring between specialist and GP by a Shared Care Guideline (SCG). If no SCG in place status reverts to red.  

Red

Red - Drugs for specialist use only, in accordance with position summary. GPs should not be asked to prescribe these products.  

Red ULM

Red ULM - Unlicensed medicines for specialist use only, in accordance with position summary. GPs should not be asked to prescribe these products.  

Grey

Grey drugs - No formal commissioning position. Check appropriate CCG /NHSE commissioning list or contact CCG/NHSE Medicines Management team for advice. Fill in individual funding request for appropriate CCG/NHSE. This will need to be signed by the Chief Pharmacist and a copy of the relevant DTC submission attached.   

Black

Black - Drugs not routinely commissioned so should not usually be prescribed  

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